Skip to Content

Disclaimer

Disclaimer
MDS makes every effort to publish accurate information on the website. "Google Translate" is provided as a free tool for visitors to read content in one's native language. Translations are not guaranteed to be 100% accurate. Neither MDS nor its employees assume liability for erroneous translations of website content.

 

International Congress of Parkinson’s Disease and Movement Disorders ®

Congress
Main Content

Plenary Session 3203

Protein Aggregate Clearance in Aging and Neurodegeneration: From Pathways to Therapies

Panel Discussion

Tuesday, October 7, 2025
8:00 - 9:30 | Room TBD

In this session, the faculty will describe mechanisms of protein aggregate clearance in aging and neurodegeneration, how protein aggregation drives progression and how this knowledge can be translated into new therapeutic approaches.


Chairs:

Gabor Kovacs, Canada
Tiago Outeiro, Germany

Presenters:

Waste Clearance and the Aging Brain
Roxana Carare, United Kingdom

The Role of Protein Aggregation on Disease Progression
Allison Kraus, USA

Therapeutic Strategies Targeting Protein Aggregation
Simone Engelender, Israel

CSPC Liaisons:

Gabor Kovacs, Canada

Learning Objectives

At the conclusion of this session, participants should be better able to:

  1. Identify the waste clearance mechanisms of the human brain in aging including glymphatics
  2. Summarize evidence that multiple protein aggregation and propagation drives progression in neurodegenerative disease
  3. Identify major therapeutic strategies targeting protein aggregates clearance

Recommended Audience

Clinician / General Neurology
Fellow / Resident / Student
Health Professional (non-physician)
Industry
Researcher / Basic Science

Education Level

Advanced / Expert
Beginner / Foundational
Intermediate / Experienced

Focus

Translational