Parallel Session 2405

Key Mechanisms in Parkinson’s Disease: From Biology to Therapy

Monday, August 28, 2023
15:00 – 17:00

 

In this session, the faculty will discuss selected pathological mechanisms in Parkinson’s disease, how they can be targeted in the present and in the future.

Chairs:
Chin-Hsien Lin, Taiwan 
Leonidas Stefanis, Greece

Mitochondrial Biology and Pathobiology
Shinji Saiki, Japan 

Lipidomics
Ulf Dettmer, USA

Lysosomal Dysfunction
Maria Xilouri, Greece 

CSPC Liaison:
Tiago Outeiro, Germany

At the conclusion of this session, participants should be better able to:

1. Discuss how mitochondrial biology and dysfunction, caused by environmental or genetic factors, is involved in Parkinson’s disease, and how this can be used as a therapeutic strategy
2. Appreciate how alterations in lipids and membranes might be at the origin of protein aggregation, and how they can be targets for intervention
3. Discuss how lysosomal dysfunction is a key cellular mechanism and what can be strategies used to improve lysosomal function in Parkinson’s disease

Recommended Audience:
Clinician, Researcher / Basic Scientist, Fellow / Resident / Student

Education Level:
Beginner/Foundational